الدكتور زيد الطعاني
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CURRENTLY I AM ACCEPTING MASTER STUDENT ... if you are interested send your cv. with 2 refrencess to email@example.com
The past decade has witnessed the discovery of endogenously
produced hydrogen sulfide (H2S) as a new signaling molecule. H2S has the ability to diffuse throw
cell membrane within milliseconds, do not need any type of receptor to modulate
its action. H2S has the ability
to act as a neurotransmitter, regulator of blood pressure, antioxidant
upregulation, immunomodulator or anti-apoptotic agent, together with its great
pharmacological potential, is now well established.
primarily focuses physical and chemical properties and physiological actions of
H2S and nitric oxide (NO). In addition to studying a novel post-translational modification induced by H2S, named S-sulfhydration (SSH of cysteine amino acid) and
its effect on modifying different cellular proteins. The S-sulfhydrated
proteins activate/deactivate many signaling pathways or regulatory proteins. A long term goal is to accelerate the
development and application of H2S -related drugs in the future.
Wright, Zaid Altaany, Yumin Bi, Zaccary Alperstein, Patrick
regulates thioredoxin reductase oligomerization and activity. Antioxidants
and Redox Signaling, Nov. 2017.
Impact factor 7.4
Módis, YoungJun Ju, Akbar Ahmad, Ashley A Untereiner, Zaid Altaany,
Lingyun Wu, Csaba Szabo, Rui Wang. (2017) S-Sulfhydration
of ATP synthase by hydrogen sulfide stimulates mitochondrial bioenergetics.
Pharmacological research. 113, 116-124. Impact factor 4.48.
- Zaid Altaany, YoungJun
Ju Guangdong Yang and Rui Wang. (2014) The coordination of S- sulfhydration,
S- nitrosylation and phosphorylation of endothelial nitric oxide synthase by
hydrogen sulfide. Science Signaling, 7, (342): ra87. Impact
- Kexin Zhao,
YoungJun Ju, Li S, Zaid Altaany, Rui Wang, Guangdong Yang. (2014) Mediation
of MEK1 S-sulfhydration and PARP-1 activation in H2S-protected DNA damage repair.
EMBO report. 2014, 15(7):792-800. Impact factor 9.05
- Zaid Altaany, Francesco
Moccia, Luca Munaron, Daniele Mancardi and Rui Wang. (2014) Hydrogen sulfide
and endothelial dysfunction: relationship with nitric oxide. Current Medicinal
Chemistry, 21(32):3646-61. Impact factor 3.85
- Zaid Altaany, Guangdong
Yang and Rui Wang. (2013) Crosstalk between hydrogen sulfide and nitric oxide
in endothelial cells. J Cell Mol Med., (7):879-88. Impact
Bucci, Andreas Papapetropoulos, Valentina Vellecco, Zongmin Zhou, Zaid Altaany, et al., (2013)
cGMP-Dependent Protein Kinase Contributes to Hydrogen sulfide-stimulated vasorelaxation.
PLoS One. 7(12):e53319. Impact factor 3.53
- Andreas Papapetropoulos, Anastasia
Pyriochou, Zaid Altaany, Guangdong
Yang, Antonia Marazioti,
Zongmin Zhou, Mark G. Jeschke, Ludwik K. Branski, David N. Herndon, Rui Wang and
(2009) Hydrogen sulfide is an endogenous stimulator of angiogenesis.
PNAS. 06(51): 21972-7. Impact factor 9.43
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Dr. Zaid Altaany
Assistant Professor in Biochemistry & Molecualr Genetics
Department of Basic Sciences
Faculty of Medicne - Yarmouk University
Tel: 02/7211111 ext. 3427